Curator's Teaching Professor of Chemistry (573) 341-6220 Fax: (573) 341-6033 yinfa@mst.edu

Education

Biography

Honors and Awards

Publications

In print and in press:

1. Hongwei Gai,Isaac Stayton, Xin Liu, Bingcheng Lin and Yinfa Ma, “Visualizing chemical interactions in life sciences with wide-field fluorescence microscopy towards the single molecule level: A minireview," Trends in Analytical Chemistry, 2007, in press.

2. Ming Du, James H. Flanagan, Jr. and Yinfa Ma, “Separation of Homo- and Heteroduplexes of DNA Fragments with Different Melting Temperature by Capillary Electrophoresis at One Single Temperature,” Journal of Capillary Electrophoresis, 2007, 10, 33-39.

3. Mary Adams, Weisheng Lin, Yinfa Ma, “Quantitative Determination of ZnO Nanoparticles in Human Bronchoalveolar Carcinoma-Derived Lung Cancer Cells”, Journal of Undergraduate Chemical Research, 2007, 6, 19-22.

4.  Weisheng Lin, Haiying Shi, Trisha May, Honglan Shi, and Yinfa Ma, “Determination of Benzyltriethyl Ammonium Chloride from Polymeric Media by Capillary Electrophoresis with Ultraviolet Absorbance Detection,” Analytica Chimica Acta, 2007, 583, 98-102.

5. Tongwen Wang, Paul Ki-souk Nam^*, Honglan Shi, and Yinfa Ma, “Compositional Monosaccharide Analysis of Transgenic Corn Glycoproteins by HPLC with Fluorescence Detection and LC/MS with Sonic Spray Ionization,” Journal of Chromatographic Science, 2007, 45, 200-206.

6. Weisheng Lin, Yue-wern Huang, Xiao-Dong Zhou, and Yinfa Ma, “In Vitro Toxicity of Silica Nanoparticles in Human Lung Cancer Cells,” Toxicology and Applied Pharmacology, 2006, 217, 252-259.

7. Weisheng Lin, Yue-wern Huang, Xiao-Dong Zhou, and Yinfa Ma, “Toxicity of Cerium Oxide Nanoparticles in Human Lung Cancer Cells,” International Journal of Toxicology, 2006, 25, 451-457.

8. Yinfa Ma, “Undergraduate Chemical Research - A Unique Learning Experience for Students,” Missouri- Journal of Undergraduate Chemical research, 2006, 8, 2-6.

9. Hongwei Gai, Qi Wang, Yinfa Ma, Bingcheng Lin, “Correlations between molecular numbers and molecular masses in an evanescent field and their applications in probing molecular interactions”, Angewandte Chemie, 2005, 44, 5107-5110.

10.  Zahra Afrasiabi, Ekk Sinn, Weisheng Lin, Yinfa Ma, Charles Campana, Subhash Padhye, "Nickel (II) complexes of naphthaquinone thiosemicarbazone and semicarbazone: Synthesis, structure, spectroscopy,and biological activity,"  Journal of Inorganic Biochemistry, 2005, 99, 1526-1531.

11.  Hongwei Gai, Ying Li, Zhanhua Silber-Li, Yinfa Ma, Bingcheng Lin, “Simultaneously measurements the velocities of particle/single molecules in bulk flow and near wall flow in microchannel,” Lab on Chip, 2005, 5, 443-449. 

12.  Guanyu Yang, Yinfa Ma, and Jie Xu,  “A Biomimetic Catalytic System Driven by Electron Transfer for Selective Oxygenation of Hydrocarbon,” J. Am. Chem. Soc., 2004, 126, 10542-10543.

13.  Yinfa Ma, Guanshu Liu, Ming Du and Isaac Stayton, “Recent Developments in the Determination of Urinary Cancer Biomarkers By Capillary Electrophoresis,” Electrophoresis, 2004, 25, 1473-1484.

14.  Hongwei Gai, Linfen Yu, Zhongpeng Dai, Yinfa Ma, Bingcheng Lin, “Hydrostatic Pressure Injection on a Microfluidic Chip,” Electrophoresis, 2004, 25, 1888-1894.

15.  Junnan Chen, Guanshu Liu, Yue-Wern Huang, Zahra Afrasiabi, Ekkehard Sinn, Yinfa Ma, “The anticancer activity and the mechanism study of 1,2 naphthoquinone thiosemicarbazone and its metal derivatives against MCF-7 human breast cancer cells,” Toxicology and Applied Pharmacology, 2004, 197, 40-48.

16.  Ming Du, Virgil Flanigan and Yinfa Ma, “Simultaneous Determination of Polyamines and Catecholamines in Cell Cultures and Biological Samples by Capillary Electrophoresis with Laser-induced Fluorescent Detector (CE-LIF),” Electrophoresis. 2004, 25, 1496-1502.

17.  Guanshu Liu, Junnan Chen, and Yinfa Ma, “Simultaneous determination of catecholamines and polyamines in PC-12 cell extracts by micellar electrokinetic capillary chromatography with ultraviolet absorbance detection," JChomatogr. B, 2004, 805, 281-288.

18. Ming Du, Wei Wu, Nuran Ercal, and Yinfa Ma, "Simultaneous Determination of 3-Nitro Tyrosine, o-, m-, and p-Tyrosine by HPLC with Pre-column Cloud Point Extraction," J. Chromatogr, B, 2004, 803, 321-329.

19.  Zahra Afrasiabi, Ekkehard Sinn, Junnan Chen, Yinfa Ma, Arnold L. Rheingold, Lev N. Zakharov, Nigam Rath and Subhash Padhye, “Appended 1,2-naphthoquinones as anticancer agents 1: synthesis, structural, spectral and antitumor activities of ortho-naphthaquinone thiosemicarbazone and its transition metal complexes,” Inorganica Chimica Acta 2004, 357 (1), 273-280.

20.  Linfen Yu, Hongwei Gai, Hongli Qi, Yuanming Gui, Yinfa Ma, Bingcheng Lin, “Electrophoretic Mobility of Carp Erythrocyte on Microfluidic Chip,” Chinese J. Anal. Chem. 2004, 32, 557-560.

In review:

1.   Weisheng Lin, Isaac Stayton, Yue-wern Huang, Xiao-Dong Zhou, and Yinfa Ma, “Cytotoxicity and Cell Membrane Depolarization Induced by Aluminum Oxide Nanoparticles in Human Lung Epithelial Cells A549”, Toxicological and Environmental Chemistry, 2007, submitted.

2.    Xue Han, Delbert E. Day, Ming Du, and Yinfa Ma, Protein Separation Using Hydroxyapatite Microspheres Made from a Borate Glass, Journal of Chromatography A, 2007, submitted.

3.   Tongwen Wang, Evelyn Chamberlain, Honglan Shi, Craig D. Adams, and Yinfa Ma,  “Analysis of Oxidation Byproducts of Dyfonate by Three Oxidants Using High Performance Liquid Chromatography Coupled with Quadrupole Ion Trap Mass Spectrometry”, Journal of Chromatography A, 2007, submitted.

4.   Tongwen Wang, Evelyn Chamberlain, Honglan Shi, Craig D. Adams, and Yinfa Ma,“Identification of Hydrolytic Metabolites of Dyfonate in Alkaline Aqueous Solutions by using High Performance Liquid Chromatography Coupled with Quadrupole Ion Trap Mass Spectrometry”, Environmental Science and Technology, 2007, submitted.

5.  Chamberlain, E., Wang, T., Ma, Y., Shi, H., Fulmer, A., Adams, C., “Comprehensive Investigation of Degradation 1 Products of Diazinon by Various Oxidation Systems and Hydrolysis Using High Performance Liquid Chromatography Coupled with Ion Trap Mass Spectrometer”, Environmental Science and Technology, 2007, submitted.

6.  Mingxun Wang, Isaac Stayton, and Yinfa Ma, “Study of DNA and Metal Oxide and Silica Nanoparticle Interactions by Monitoring DNA Melting”, The Journal of Undergraduate Chemistry Research, 2007, submitted.

Advising

Undergraduate students (4):

Campbell, Christopher Thomas,
Ceballos, Miranda C.
Breckenridge, Julie M.
Chad Smith

Ph.D. Graduate Students (6):

Stephen Gibbons    Ph.D. (~2006)
Thesis Title: Early Lung Cancer Diagnosis by Using Urinary Pteridines as Fingerprints with Capillary Electrophoresis - Laser Induced Fluorescence Detection. 

Isaac Stayton       Ph.D. (~2006)
Thesis Title: Study of Interactions of Carcinogen Molecules with Cells at Single Cell and Single Molecule Level

Tongwen Wang     Ph.D. (~2007)
Thesis Title: HPLC-MS study of Glycoproteins in Transgenic Corn

Weisheng Lin       Ph.D. (~2007)
Thesis Title: Study of Cellular Toxicity of Newly Developed Anticancer Drugs and Selected  Nanoparticles on MCF-7 Breast Cancer Cells      

Yongqing Jiang     Ph.D. (~2008)
Thesis Title: Development of Early Cancer Diagnosis Techniques by Using Variety of Biomarkers in Blood

Xiaoqian Liu       Ph.D. (~2008)
Thesis Title: Assessment of Oxidative Stress Effect of Nanoparticles on Lung Cancer Cells by Using Various Biomarkers

Chuan Wang        Ph.D. (~2010)
Thesis Title: Cytotoxicity of newly synthesized anticancer drugs

Xiaoliang Cheng    Ph.D. (~2010)
Thesis Title:New nanomaterials for anticancer drug delivery

MS Graduate Students:  None

Post-doctors and visiting professors:

Yanru Chen - Visiting professor, Nanjing Institute of Science and Technology, China (September, 2005 March 2006)

Ming Du --- Postdoctoral fellow (September 1, 2001 - September 30, 2004

Heng Liang - Visiting professor (March 12 - Present), Xi’an Jiaotong University, China

Graduate Students Graduated Last Year:

Junnan Chen     MS in Chemistry
Thesis Title: Glycoproetin Characterization by HPLC-ESI-MS and Anticancer Drug Screening and Mechanism Study

Guanshu Liu     MS in Chemistry
Thesis Title: Capillary Electrophoresis and Its Applications in the Biological Science: Co-Enzyme A, Polyamines and Catecholamine

(Sitzes, Granich)